m-Chloroperbenzoic acid → 2-(2-Pyridylmethyl)-1H-isoindole-1,3(2H)-dione N-oxide
반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][N:8]1[C:16](=[O:17])[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]1=[O:18].ClC1C=CC=C(C(OO)=[O:27])C=1>C(Cl)(Cl)Cl>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][N+:8]1([O-:27])[C:16](=[O:17])[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]1=[O:18]참가 물질
4
실험 절차
2-(2-Pyridylmethyl)-1H-isoindole-1,3(2H)-dione (7.5 g, 32 mmol) and 3-chloroperbenzoic acid (77%, 14.3 g, 64 mmol) were dissolved in chloroform (250 ml), and the mixture was stirred at room temperature for 20 hrs. The solvent was evaporated, and the residue was washed with ethyl acetate to give the titled compound (8.0 g, 99%) as white crystals.
후처리
- customThe solvent was evaporated
- washthe residue was washed with ethyl acetate
출처 및 근거
- ORD 기록
- ord-6a540c640f6a44cea2dc197dab134bc1
- 출처 데이터셋
- uspto-grants-2010_08
- 특허 번호
- US07767665B2
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