Acetic Anhydride → 3-(2-Pyridyl)propyl acetate
반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][CH2:8][CH2:9][OH:10].[C:11](OC(=O)C)(=[O:13])[CH3:12]>N1C=CC=CC=1>[C:11]([O:10][CH2:9][CH2:8][CH2:7][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=1)(=[O:13])[CH3:12]참가 물질
4
실험 절차
2-Pyridinepropanol (2.0 g, 14.6 mmol) was dissolved in pyridine (5 ml), and acetic anhydride (3.0 g, 29.2 mmol) was added thereto. The reaction mixture was stirred at room temperature for 2.5 hrs, and subjected to a silica gel (75 g) column chromatography. The fractions eluted with hexane-ethyl acetate (3:1, v/v) were collected and concentrated to give the titled compound (2.6 g, 99%).
후처리
- washThe fractions eluted with hexane-ethyl acetate (3:1
- customv/v) were collected
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-c448b787721b4073b3743c225cff8fc7
- 출처 데이터셋
- uspto-grants-2010_08
- 특허 번호
- US07767665B2
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