Phenol → 4'-Phenoxyacetophenone

HRID 501267

반응식

[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:8][C:9](N(C)C)=[O:10]>>[CH3:8][C:9]([C:4]1[CH:5]=[CH:6][C:1]([O:7][C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[CH:2][CH:3]=1)=[O:10]

참가 물질

반응물 2

HCID 996Phenol

HCID 31374Dimethylacetamide

생성물 1

HCID 2367834'-Phenoxyacetophenone

실험 절차

4-Phenoxyacetophenone was prepared by refluxing 4-fluoroaceotone and phenol in DMAc for 16 hours. The solvent was removed under reduced pressure and the reside subjected to standard ethyl acetate/water work-up and the resulting material purified by silica gel chromatography.

후처리

temperatureby refluxing 4-fluoroaceotone
customThe solvent was removed under reduced pressure
customthe resulting material purified by silica gel chromatography

출처 및 근거

ORD 기록: ord-2336461666234a08953253d8164eb22e
출처 데이터셋: uspto-grants-2010_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07772260B2

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