Acetic Anhydride → N-(3-fluoro-2-methylphenyl)acetamide
반응식
[F:1][C:2]1[C:3]([CH3:9])=[C:4]([CH:6]=[CH:7][CH:8]=1)[NH2:5].[C:10](OC(=O)C)(=[O:12])[CH3:11]>CCO>[F:1][C:2]1[C:3]([CH3:9])=[C:4]([NH:5][C:10](=[O:12])[CH3:11])[CH:6]=[CH:7][CH:8]=1참가 물질
4
실험 절차
To a solution of 3-fluoro-2-methylaniline (2.65 g, 21.2 mmol) in EtOH (25 mL) at 0° C. was added acetic anhydride (2.60 g, 25.5 mmol). The mixture was stirred at rt overnight then concentrated under reduced pressure to give the title compound (3.54 g). LCMS: m/z 168[M+H]+
후처리
- concentrationthen concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-bf3334cd362b4b6bb79702f5c40e07d9
- 출처 데이터셋
- uspto-grants-2010_08
- 특허 번호
- US07772267B2
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