Acetic Acid → 2-Bromo-5-tert-butyl-1,3-dimethylbenzene

HRID 501870

반응식

HRID 501870 반응식
C(O)(=O)C.[C:5]([C:9]1[CH:10]=[C:11]([CH3:16])[CH:12]=[C:13]([CH3:15])[CH:14]=1)([CH3:8])([CH3:7])[CH3:6].[Br:17]Br>O>[C:5]([C:9]1[CH:10]=[C:11]([CH3:16])[C:12]([Br:17])=[C:13]([CH3:15])[CH:14]=1)([CH3:8])([CH3:7])[CH3:6]

참가 물질

5

반응물 3

HCID 176Acetic AcidHCID 73785-Tert-butyl-m-xyleneHCID 24408Bromine

생성물 1

HCID 2203642-Bromo-5-tert-butyl-1,3-dimethylbenzene수율 94.7%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Under an inert atmosphere, 225 g of acetic acid was put into a 500 ml three-necked flask, and 24.3 g of 5-t-butyl-m-xylene was added. Then, after adding 31.2 g of bromine, it was reacted at 15-20° C. for 3 hours. The reaction liquid was added to 500 ml of water, and the deposited precipitate was filtrated. It was washed with 250 ml of water twice and 34.2 g of white solid was obtained.

후처리

  1. customwas reacted at 15-20° C. for 3 hours
  2. customThe reaction liquid
  3. filtrationthe deposited precipitate was filtrated
  4. washIt was washed with 250 ml of water twice

출처 및 근거

ORD 기록
ord-bda8c24223b24e88ad61a1e994bf420d
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07772360B2

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