반응식
[CH3:1][O:2][CH2:3][C:4]#[N:5].C([OH:8])C.[ClH:9].[CH2:10]([O:12][CH2:13]C)C>>[ClH:9].[CH3:10][O:12][CH2:13][C:1]([O:2][CH2:3][CH:4]=[NH:5])=[O:8]참가 물질
5
실험 절차
A solution of 35.5 g (0.50 mol) of methoxyacetonitrile in 29 mL (23 g, 0.50 mol) of ethanol and 30 mL of absolute diethylether was cooled to 0° C. and over 1 hour 22.5 g (0.62 mol) of hydrogen chloride gas was introduced, whilst towards the end of the introduction of gas the reaction product crystallized out. To complete the precipitation 130 mL of diethylether were added and the colorless needles were filtered off. Yield: 66.4 g (86% of theory); melting point: 117° C.-118° C.
후처리
- additionwas introduced, whilst towards the end of the introduction of gas the reaction product
- customcrystallized out
- customthe precipitation 130 mL of diethylether
- additionwere added
- filtrationthe colorless needles were filtered off
출처 및 근거
- ORD 기록
- ord-e4097f5d8b4a439a99ee79dba119e741
- 출처 데이터셋
- uspto-grants-2004_03
- 특허 번호
- US06710055B2
연결된 노트
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