Hydrazine hydrate (1:1) → 1H-pyrrole-2-carbohydrazonamide
반응식
[NH:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]#[N:7].C[O-].[Na+].O.[NH2:12][NH2:13]>C(O)C.O>[NH:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6](=[N:12][NH2:13])[NH2:7]참가 물질
6
실험 절차
A solution of 10 g 1H-pyrrole-2-carbonitrile and 1 eq sodium methoxide in 20 ml ethanol and stirred for 10 min. Hydrazine hydrate (3 eq.) is then added and resulting reaction mixture is stirred at room temperature for 18 h. The Reaction mixture is then diluted with water, extracted with ethyl acetate, dried over Na2SO4 and concentrated under vacuum to yield desired compound.
후처리
- customresulting
- customreaction mixture
- extractionextracted with ethyl acetate
- dry with materialdried over Na2SO4
- concentrationconcentrated under vacuum
출처 및 근거
- ORD 기록
- ord-e3f6ae66f714449492a1fc650b79c8ba
- 출처 데이터셋
- uspto-grants-2010_08
- 특허 번호
- US07776864B2
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