Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Lovastatin → Lovastatin Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Lovastatin | HCID 53232 | — |
| 반응물 | 3,5-Dihydroxypentanoic acid | HCID 322588 | — |
| 생성물 | Lovastatin Acid | HCID 64727 | — |
반응 단계
For example, lovastatin (Ia) is prepared by lactonisation of the 3,5-dihydroxy pentanoic acid derivative (II) to (Ia) either by heating in an organic solvent or in the presence of an acid catalyst. The former, viz. mevinolinic acid, is obtained from a fermentation broth containing Asperigillus Terreus.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07777056B2 |
| 출처 데이터셋 | uspto-grants-2010_08 |
| ORD ID | ord-5c4d68f7bdef48c8b8ecd2e2f3a1a222 |
| 출처 메모 | uspto-grants-2010_08 |