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HRID504055

反应详情

EQUATION

反应方程式

HRID 504055 的结构方程式

REACTANTS

反应物

2
结构：CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@H]21
HCID53232

Lovastatin

C24H36O5

结构：O=C(O)CC(O)CCO
HCID322588

3,5-dihydroxypentanoic acid

C5H10O4

PRODUCTS

生成物

1
结构：CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(=O)O)[C@H]21
HCID64727

Lovastatin acid

C24H38O6

PROCEDURE

实验过程

For example, lovastatin (Ia) is prepared by lactonisation of the 3,5-dihydroxy pentanoic acid derivative (II) to (Ia) either by heating in an organic solvent or in the presence of an acid catalyst. The former, viz. mevinolinic acid, is obtained from a fermentation broth containing Asperigillus Terreus.

WORKUP

后处理

  1. temperatureby heating in an organic solvent or in the presence of an acid catalyst