Triethylamine → Ethyl [(phenoxycarbonyl)oxy]acetate
반응식
Cl[C:2]([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:3].[C:11]([O:15][CH2:16][CH3:17])(=[O:14])[CH2:12][OH:13].C(N(CC)CC)C>C1(C)C=CC=CC=1>[O:4]([C:2]([O:13][CH2:12][C:11]([O:15][CH2:16][CH3:17])=[O:14])=[O:3])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1참가 물질
5
실험 절차
13.5 ml (105.6 mmol) of phenyl chloroformate are added, dropwise, at ambient temperature to a solution of 10 g (96.15 mmol) of ethyl glycolate and 27 ml (192.3 mmol) of triethylamine in 20 ml of toluene and the mixture is stirred at ambient temperature for 2 h. The salt formed is separated and the filtrate is concentrated under reduced pressure to obtain 20 g of oily product, which are used without modification in the following step.
후처리
- customThe salt formed
- customis separated
- concentrationthe filtrate is concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-bbd48102c7484f56a47adf9e6ebbdf53
- 출처 데이터셋
- uspto-grants-2010_08
- 특허 번호
- US07777057B2
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