Diethyl(4-nitrophenyl)phosphonate → P-(4-Nitrophenyl)phosphonic acid

HRID 511220

반응식

HRID 511220 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([P:10](=[O:17])([O:14]CC)[O:11]CC)=[CH:6][CH:5]=1)([O-:3])=[O:2]>Cl>[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([P:10](=[O:11])([OH:14])[OH:17])=[CH:8][CH:9]=1)([O-:3])=[O:2]

참가 물질

3

반응물 1

HCID 284865Diethyl(4-nitrophenyl)phosphonate

생성물 1

HCID 196997P-(4-Nitrophenyl)phosphonic acid수율 100%

시약·촉매·용매 1

HCID 313Hydrochloric Acid용매

실험 절차

A solution of diethyl (4-nitrophenyl)phosphonate (60 g, 230 mmol) in 250 mL of concentrated HCl (aq) was stirred at reflux overnight. The excess HCl was removed under reduced pressure and the product used in further chemistries without purification (46.8 g, yield: 100%).

후처리

  1. temperatureat reflux overnight
  2. customThe excess HCl was removed under reduced pressure
  3. customthe product used in further chemistries without purification (46.8 g, yield: 100%)

출처 및 근거

ORD 기록
ord-00ef7beb8b9644988eeff1d44a1fe193
출처 데이터셋
uspto-grants-2015_08
특허 번호
US09096624B2

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