2-(Trifluoromethyl)pyridine-4-boronic acid → 1-[1-(4-Cyano-phenyl)-ethyl]-2-methyl-4-oxo-2'-trifluoromethyl-1,4-dihydro-[3,4']bipyridinyl-5-carboxylic acid

반응식

C(C1C=CC(CN2C(C)=C(C3C=CC=C(C(F)(F)F)C=3)C(=O)C(C(O)=O)=C2)=CC=1)#N.[F:31][C:32]([F:43])([F:42])[C:33]1[CH:38]=[C:37](B(O)O)[CH:36]=[CH:35][N:34]=1.BrC1C(=O)C(C(O)=O)=CN(CC2C=CC(C#N)=CC=2)C=1C.Br[C:66]1[C:67](=[O:86])[C:68]([C:83]([OH:85])=[O:84])=[CH:69][N:70]([CH:73]([C:75]2[CH:80]=[CH:79][C:78]([C:81]#[N:82])=[CH:77][CH:76]=2)[CH3:74])[C:71]=1[CH3:72]>>[C:81]([C:78]1[CH:77]=[CH:76][C:75]([CH:73]([N:70]2[CH:69]=[C:68]([C:83]([OH:85])=[O:84])[C:67](=[O:86])[C:66]([C:37]3[CH:36]=[CH:35][N:34]=[C:33]([C:32]([F:43])([F:42])[F:31])[CH:38]=3)=[C:71]2[CH3:72])[CH3:74])=[CH:80][CH:79]=1)#[N:82]