3-Phenoxytoluene → 1-Bromo-2-methyl-4-phenoxybenzene
반응식
[O:1]([C:8]1[CH:9]=[C:10]([CH3:14])[CH:11]=[CH:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:15]N1C(=O)CCC1=O>C(#N)C>[C:2]1([O:1][C:8]2[CH:13]=[CH:12][C:11]([Br:15])=[C:10]([CH3:14])[CH:9]=2)[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1참가 물질
4
실험 절차
A mixture of 3-phenoxytoluene (2.5 g, 0.0136 mol) and N-bromosuccinimide (2.54 g, 0.0142 mol) was stirred in acetonitrile (20 mL) for 2.5 hours under an atmosphere of nitrogen. The solvent was removed under reduced pressure. Carbon tetrachloride was added to the residue and the resulting solid was removed by filtration. The filtrate was concentrated to yield 4-bromo-3-methylphenyl phenyl ether as yellow oil (3.5 g, 0.0133 mol):
후처리
- customThe solvent was removed under reduced pressure
- additionCarbon tetrachloride was added to the residue
- customthe resulting solid was removed by filtration
- concentrationThe filtrate was concentrated
출처 및 근거
- ORD 기록
- ord-41372e57b62d4ee7b9f74314c3d1de09
- 출처 데이터셋
- uspto-grants-2004_03
- 특허 번호
- US06713474B2
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