Methyl 4-bromobenzoate → 4-Bromobenzohydrazide

HRID 516477

반응식

HRID 516477 반응식
C[O:2][C:3](=O)[C:4]1[CH:9]=[CH:8][C:7]([Br:10])=[CH:6][CH:5]=1.O.[NH2:13][NH2:14]>C(O)C>[Br:10][C:7]1[CH:8]=[CH:9][C:4]([C:3]([NH:13][NH2:14])=[O:2])=[CH:5][CH:6]=1

참가 물질

4

반응물 2

HCID 12081Methyl 4-bromobenzoateHCID 24654Hydrazine hydrate (1:1)

생성물 1

HCID 222194-Bromobenzohydrazide수율 67%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

First, 3.0 g (13.9 mmol) of methyl-4-bromobenzoate was put in a 100-mL three-neck flask, 10 mL of ethanol was added thereto, and the mixture was stirred. Thereafter, 4.0 mL of hydrazine monohydrate was added thereto, and the mixture was heated and stirred at 78° C. for 5 hours. The obtained solid was washed with water and collected by suction filtration; thus, 2.0 g of a white solid of 4-bromobenzohydrazide that was an object was obtained in the yield of 67%.

후처리

  1. temperaturethe mixture was heated
  2. stirringstirred at 78° C. for 5 hours
  3. washThe obtained solid was washed with water
  4. filtrationcollected by suction filtration
  5. customwas obtained in the yield of 67%

출처 및 근거

ORD 기록
ord-b7a9aeaee135487680a28efcce79c560
출처 데이터셋
uspto-grants-2015_08
특허 번호
US09112170B2

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