반응식
[CH3:1][N:2]1[CH2:23][CH2:22][C:5]2[N:6]([CH2:14][CH2:15][CH2:16][C:17](OCC)=[O:18])[C:7]3[CH:8]=[CH:9][C:10]([CH3:13])=[CH:11][C:12]=3[C:4]=2[CH2:3]1.[CH2:24]([NH2:26])[CH3:25]>>[CH2:24]([NH:26][C:17](=[O:18])[CH2:16][CH2:15][CH2:14][N:6]1[C:7]2[CH:8]=[CH:9][C:10]([CH3:13])=[CH:11][C:12]=2[C:4]2[CH2:3][N:2]([CH3:1])[CH2:23][CH2:22][C:5]1=2)[CH3:25]참가 물질
3
실험 절차
Ethyl 4-(1,2,3,4-tetrahydro-2,8-dimethylpyrido[4,3-b]indol-5-yl)butanoate (80 mg, 0.2 mmol) was stirred with ethylamine (0.8 ml) at 100-120° C. for 3-4 h to obtain 40 mg of N-ethyl-4-(1,2,3,4-tetrahydro-2,8-dimethylpyrido[4,3-b]indol-5-yl)butanamide after purification on neutral alumina chromatography eluting with methanol-dichloromethane gradient.
출처 및 근거
- ORD 기록
- ord-1be6e4c238fc4db9a7596231619a4c91
- 출처 데이터셋
- uspto-grants-2015_08
- 특허 번호
- US09115137B2
연결된 노트
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