Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethylamine → N-ethyl-4-(1,2,3,4-tetrahydro-2,8-dimethylpyrido[4,3-b]indol-5-yl)butanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethylamine | HCID 6341 | — |
| 반응물 | Ethyl 4-(1,2,3,4-tetrahydro-2,8-dimethylpyrido[4,3-b]indol-5-yl)butanoate | HCID 44159096 | — |
| 생성물 | N-ethyl-4-(1,2,3,4-tetrahydro-2,8-dimethylpyrido[4,3-b]indol-5-yl)butanamide | HCID 44159097 | — |
반응 단계
Ethyl 4-(1,2,3,4-tetrahydro-2,8-dimethylpyrido[4,3-b]indol-5-yl)butanoate (80 mg, 0.2 mmol) was stirred with ethylamine (0.8 ml) at 100-120° C. for 3-4 h to obtain 40 mg of N-ethyl-4-(1,2,3,4-tetrahydro-2,8-dimethylpyrido[4,3-b]indol-5-yl)butanamide after purification on neutral alumina chromatography eluting with methanol-dichloromethane gradient.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09115137B2 |
| 출처 데이터셋 | uspto-grants-2015_08 |
| ORD ID | ord-1be6e4c238fc4db9a7596231619a4c91 |
| 출처 메모 | uspto-grants-2015_08 |