1,8-Dichloroanthraquinone → 1,8-Bis{[2-(dimethylamino)ethyl]amino}anthracene-9,10-dione

HRID 522935

반응식

HRID 522935 반응식
Cl[C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][C:12]=3Cl)[C:7](=[O:18])[C:6]=2[CH:5]=[CH:4][CH:3]=1.[CH3:19][N:20]([CH3:24])[CH2:21][CH2:22][NH2:23]>O>[CH3:19][N:20]([CH3:24])[CH2:21][CH2:22][NH:23][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][C:12]=3[NH:23][CH2:22][CH2:21][N:20]([CH3:24])[CH3:19])[C:7](=[O:18])[C:6]=2[CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 67081,8-DichloroanthraquinoneHCID 66053N,N-Dimethylethylenediamine

생성물 1

HCID 143201191,8-Bis{[2-(dimethylamino)ethyl]amino}anthracene-9,10-dione

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture of 1,8-dichloroanthraquinone (5.5 g, 20 mmol) and N,N-dimethylethylenediamine (40 mL) was refluxed for 18 h. The mixture was cooled to room temperature and diluted with water to precipitate the title compound which was recrystallised from methanol to afford Compound 6 (4.5 g). The structure of Compound 6 is given below:

후처리

  1. temperaturewas refluxed for 18 h
  2. customto precipitate the title compound which
  3. customwas recrystallised from methanol

출처 및 근거

ORD 기록
ord-0272c4eb373b4ee89275b9904cf25ac8
출처 데이터셋
uspto-grants-2016_05
특허 번호
US09334281B2

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