Dimethylamine, hydrochloride → 3-Chloro-N,N-dimethylisoquinoline-6-carboxamide

반응식

[Cl:1][C:2]1[N:3]=[CH:4][C:5]2[C:10]([CH:11]=1)=[CH:9][C:8]([C:12]([OH:14])=O)=[CH:7][CH:6]=2.Cl.[CH3:16][NH:17][CH3:18]>>[Cl:1][C:2]1[N:3]=[CH:4][C:5]2[C:10]([CH:11]=1)=[CH:9][C:8]([C:12]([N:17]([CH3:18])[CH3:16])=[O:14])=[CH:7][CH:6]=2

참가 물질

반응물 2

HCID 10473Dimethylamine, hydrochloride

HCID 754120363-Chloroisoquinoline-6-carboxylic acid

생성물 1

HCID 899955803-Chloro-N,N-dimethylisoquinoline-6-carboxamide

실험 절차

The title compound was prepared according to the method described for Preparation 52 using 3-chloroisoquinoline-6-carboxylic acid (Preparation 54) and dimethylamine hydrochloride.

출처 및 근거

ORD 기록: ord-777df17d2f004d5bbc6803a395a55156
출처 데이터셋: uspto-grants-2016_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09334286B2

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