Ethylenediamine → Pixantrone

HRID 52402

반응식

HRID 52402 반응식
F[C:2]1[C:7]2[C:8](=[O:17])[C:9]3[CH:10]=[CH:11][N:12]=[CH:13][C:14]=3[C:15](=[O:16])[C:6]=2[C:5](F)=[CH:4][CH:3]=1.[CH2:19]([NH2:22])[CH2:20][NH2:21]>>[NH2:21][CH2:20][CH2:19][NH:22][C:2]1[C:7]2[C:8](=[O:17])[C:9]3[CH:10]=[CH:11][N:12]=[CH:13][C:14]=3[C:15](=[O:16])[C:6]=2[C:5]([NH:21][CH2:20][CH2:19][NH2:22])=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 3301EthylenediamineHCID 101059046,9-Difluorobenzo[g]isoquinoline-5,10-dione

생성물 1

HCID 134019Pixantrone

실험 절차

The reported synthetic procedures use, as a key intermediate, 6,9-difluorobenzo[g]isoquinoline-5,10-dione.- This compound is reacted with ethylene-diamine which produces the desired 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione.

출처 및 근거

ORD 기록
ord-b654eeb8ac7744adbf5d08a2d4108f4c
출처 데이터셋
uspto-grants-1997_04
특허 번호
US05616709

연결된 노트

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