Hydrochloric Acid → 3-(5H-tetrazol-5-yl)morpholine hydrochloride

HRID 524759노트

반응식

HRID 524759 반응식
[N:1]1[CH:5]([CH:6]2[CH2:11][O:10][CH2:9][CH2:8][N:7]2C(OC(C)(C)C)=O)[N:4]=[N:3][N:2]=1.[ClH:19]>CCOC(C)=O>[ClH:19].[N:4]1[CH:5]([CH:6]2[CH2:11][O:10][CH2:9][CH2:8][NH:7]2)[N:1]=[N:2][N:3]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 90043836Tert-butyl 3-(5H-tetrazol-5-yl)morpholine-4-carboxylate

생성물 1

HCID 900434363-(5H-tetrazol-5-yl)morpholine hydrochloride수율 70%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

Tert-butyl 3-(5H-tetrazol-5-yl)morpholine-4-carboxylate (2 g, 7.8 mmol) was reacted with a solution of HCl in EtOAc (6 mol/L, 30 mL) according to the procedure as described in Example 18, Step B to give the title compound as a grey solid (1.05 g, 70%). The compound was characterized by the following spectroscopic data:

출처 및 근거

ORD 기록
ord-6e912af3ea4548d89de5bb12d015fa50
출처 데이터셋
uspto-grants-2016_05
특허 번호
US09340538B2

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