Sodium Hydroxide → 4-Methylpiperazine-2-carboxylic acid

HRID 524780노트

반응식

HRID 524780 반응식
[CH3:1][N:2]1[CH2:7][CH2:6][NH:5][CH:4]([C:8]([O:10]CC)=[O:9])[CH2:3]1.[OH-].[Na+]>>[CH3:1][N:2]1[CH2:7][CH2:6][NH:5][CH:4]([C:8]([OH:10])=[O:9])[CH2:3]1

참가 물질

3

반응물 2

HCID 14798Sodium HydroxideHCID 12558522Ethyl 4-methylpiperazine-2-carboxylate

생성물 1

HCID 64209034-Methylpiperazine-2-carboxylic acid수율 100%

실험 절차

Ethyl 4-methylpiperazine-2-carboxylate (1.03 g, 6 mmol) was reacted with NaOH (0.48 g, 12 mmol) according to the procedure as described in Example 21, Step A to give the title compound as colorless oil (0.86 g, 100%). The compound was characterized by the following spectroscopic data:

출처 및 근거

ORD 기록
ord-88397e1baa204780b98e954df8ed3c75
출처 데이터셋
uspto-grants-2016_05
특허 번호
US09340538B2

반응 노트

불러오는 중…