Ammonium Chloride → 6-Methoxybenzo[d]thiazole-2-carboximidamide hydrochloride

HRID 524801

반응식

HRID 524801 반응식
[CH3:1][O:2][C:3]1[CH:13]=[CH:12][C:6]2[N:7]=[C:8]([C:10]#[N:11])[S:9][C:5]=2[CH:4]=1.C[O-].[Na+].[Cl-:17].[NH4+:18]>>[ClH:17].[CH3:1][O:2][C:3]1[CH:13]=[CH:12][C:6]2[N:7]=[C:8]([C:10](=[NH:18])[NH2:11])[S:9][C:5]=2[CH:4]=1

참가 물질

4

반응물 3

HCID 25517Ammonium ChlorideHCID 3421092-Cyano-6-methoxy benzothiazoleHCID 10942334Sodium Methoxide

생성물 1

HCID 1181076136-Methoxybenzo[d]thiazole-2-carboximidamide hydrochloride수율 75%

실험 절차

6-methoxybenzo[d]thiazole-2-carbonitrile (1 g, 5.26 mmol) was reacted with sodium methoxide (0.28 g, 5.26 mmol) and ammonium chloride (0.6 g, 11 mmol) according to the procedure as described in Example 61, Step B to give the title compound as a white solid (0.96 g, 75%). The compound was characterized by the following spectroscopic data:

출처 및 근거

ORD 기록
ord-a5da7ede6b604060ad6e1da9b0089605
출처 데이터셋
uspto-grants-2016_05
특허 번호
US09340538B2

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