5-Methoxy-1,3-thiazol-2-amine → 5-Methoxythiazole-2-carbonitrile

HRID 524802노트

반응식

HRID 524802 반응식
[CH3:1][O:2][C:3]1[S:7][C:6](N)=[N:5][CH:4]=1.[C:9]([Cu])#[N:10]>>[CH3:1][O:2][C:3]1[S:7][C:6]([C:9]#[N:10])=[N:5][CH:4]=1

참가 물질

3

반응물 2

HCID 203162835-Methoxy-1,3-thiazol-2-amineHCID 178418546HCID 178418546, 화합물

생성물 1

HCID 900443835-Methoxythiazole-2-carbonitrile수율 30%

실험 절차

5-methoxythiazol-2-amine (2.6 g, 20 mmol) was reacted with CuCN (4 g, 44 mmol) according to the procedure as described in Example 61, Step A to give the title compound as brownish oil (0.84 g, 30%). The compound was characterized by the following spectroscopic data:

출처 및 근거

ORD 기록
ord-b60f1450e100498aa2dcb7364c0119c2
출처 데이터셋
uspto-grants-2016_05
특허 번호
US09340538B2

반응 노트

불러오는 중…