Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,5-Dichloroaniline → 3-Bromo-N-(3,5-dichlorophenyl)-1-(phenylsulfonyl)-1H-pyrrole-2-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,5-Dichloroaniline | HCID 12281 | — |
| 반응물 | Methyl 3-bromo-1-(phenylsulfonyl)-1H-pyrrole-2-carboxylate | HCID 44518095 | — |
| 생성물 | 3-Bromo-N-(3,5-dichlorophenyl)-1-(phenylsulfonyl)-1H-pyrrole-2-carboxamide | HCID 70981361 | 96% |
반응 단계
Prepared from 2.00 g (5.81 mmol) of methyl 3-bromo-1-(phenylsulfonyl)-1H-pyrrole-2-carboxylate and 2.82 g (17.41 mmol) of 3,5-dichloroaniline following the experimental procedure described in Preparation 44a. The product was purified by flash chromatography (0% to 40% hexane/AcOEt) to give 2.64 g (96% yield) of the title compound as a beige solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09340547B2 |
| 출처 데이터셋 | uspto-grants-2016_05 |
| ORD ID | ord-163acc9cf55841f98c7120bd0d8683c0 |
| 출처 메모 | uspto-grants-2016_05 |