Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5,5-Diphenylhydantoin → 3-[(3-Cyanophenyl)methyl]-4,5-dihydro-5,5-diphenyl-1H-imidazol-2,4(3H)-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5,5-Diphenylhydantoin | HCID 1775 | — |
| 반응물 | Benzonitrile, 3-(bromomethyl)- | HCID 97249 | — |
| 반응물 | Potassium tert-butoxide | HCID 23665647 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 3-[(3-Cyanophenyl)methyl]-4,5-dihydro-5,5-diphenyl-1H-imidazol-2,4(3H)-dione | HCID 18975921 | — |
반응 단계
Prepared by reacting 25.5 g (0.101 Mol) of 5,5-diphenylhydantoin with 21.15 g (0.108 Mol) of 3-(bromomethyl)-benzonitrile in the presence of 12.0 g (0.107 Mol) of potassium tert.-butoxide and 200 ml of anhydrous dimethylformamide. After conventional working up 34.0 g (92% of theory) of colourless crystals were obtained, mp. 160°-164° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05616620 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-2c4e7f36e9c3472cb708dcb2ea44cdc0 |
| 출처 메모 | uspto-grants-1997_04 |