8-Boc-3,8-diaza-bicyclo(3.2.1)octane → HCID 57477265, 화합물

HRID 527878

반응식

HRID 527878 반응식
[C:1]([O:5][C:6]([N:8]1[CH2:15][CH2:14][N:13]([C:16]2[C:17]3[CH:24]=[CH:23][NH:22][C:18]=3[N:19]=[CH:20][N:21]=2)[CH2:12][C:9]21[CH2:11][CH2:10]2)=[O:7])([CH3:4])([CH3:3])[CH3:2].C(OC(N1C2CCC1CNC2)=O)(C)(C)C.C(OC(N1CCNCC21CC2)=O)(C)(C)C>>[C:1]([O:5][C:6]([N:8]1[CH:9]2[CH2:10][CH2:11][CH:15]1[CH2:14][N:13]([C:16]1[C:17]3[CH:24]=[CH:23][NH:22][C:18]=3[N:19]=[CH:20][N:21]=1)[CH2:12]2)=[O:7])([CH3:3])([CH3:4])[CH3:2]

참가 물질

4

반응물 3

HCID 157409088-Boc-3,8-diaza-bicyclo(3.2.1)octaneHCID 51358567tert-Butyl 4,7-diazaspiro(2.5)octane-4-carboxylateHCID 574772807-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,7-diazaspiro[2.5]octane-4-carboxylic acid tert-butyl ester

생성물 1

HCID 57477265HCID 57477265, 화합물

실험 절차

Prepared in a way similar to Intermediate 1, using 3,8-diaza-bicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester, instead of 4,7-diaza-spiro[2.5]octane-4-carboxylic acid tert-butyl ester.

출처 및 근거

ORD 기록
ord-480b82ed36624265aaf7d516d070a956
출처 데이터셋
uspto-grants-2016_05
특허 번호
US09346809B2

연결된 노트

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