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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 528524생성일: 2026년 10월 25일

N-[(4-methoxyphenyl)methyl]-1,3-thiazol-2-amine → 4-(2-chloro-4-(trifluoromethyl)phenyl)-N-(4-methoxybenzyl)-N-(thiazol-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonamide

https://huagongshe.com/reaction/528524

반응식

참여 물질

역할이름HCID투입량
반응물N-[(4-methoxyphenyl)methyl]-1,3-thiazol-2-amineHCID 578640—
반응물4-(2-chloro-4-(trifluoromethyl)phenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonyl chlorideHCID 89761722—
생성물4-(2-chloro-4-(trifluoromethyl)phenyl)-N-(4-methoxybenzyl)-N-(thiazol-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonamideHCID 89761797—

반응 단계

4-(2-chloro-4-(trifluoromethyl)phenyl)-N-(4-methoxybenzyl)-N-(thiazol-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonamide (INTERMEDIATE X) was prepared in the same manner as INTERMEDIATE D, STEP 3, except employing INTERMEDIATE E and INTERMEDIATE W (N-(4-methoxybenzyl)thiazol-2-amine) m/z (ESI) 595.8 (M+H)+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09346798B2
출처 데이터셋uspto-grants-2016_05
ORD IDord-7a04a9f9cab54a2e966ebf8f48210abf
출처 메모uspto-grants-2016_05