Hydrochloric Acid → Hydrochloric Acid

HRID 528737노트

반응식

HRID 528737 반응식
C(OC([N:8]1[CH2:11][CH:10]([C:12]2[S:13][CH:14]=[C:15]([CH3:17])[N:16]=2)[CH2:9]1)=O)(C)(C)C.[ClH:18]>O1CCOCC1>[ClH:18].[NH:8]1[CH2:11][CH:10]([C:12]2[S:13][CH:14]=[C:15]([CH3:17])[N:16]=2)[CH2:9]1.[ClH:18]

참가 물질

5

반응물 2

HCID 313Hydrochloric AcidHCID 67979293HCID 67979293, 화합물

생성물 2

HCID 313Hydrochloric AcidHCID 674586202-(Azetidin-3-yl)-4-methylthiazole HCl

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

To 47 mg (0.18 mmol) 3-(4-methyl-thiazol-2-yl)-azetidine-1-carboxylic acid tert-butyl ester was added 2 mL (8 mmol) HCl in dioxane (4 M), and the reaction was stirred at room temperature for 1 hour. The solvent was evaporated to give the desired product as a HCl salt, which was used in the next step without further purification.

후처리

  1. customThe solvent was evaporated

출처 및 근거

ORD 기록
ord-79939fb751a84bdd853336af31256344
출처 데이터셋
uspto-grants-2016_05
특허 번호
US09346816B2

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