Methyl iodide → 3-Methoxy-2-nitropyridine

HRID 529171

반응식

HRID 529171 반응식
[N+:1]([C:4]1[C:9]([OH:10])=[CH:8][CH:7]=[CH:6][N:5]=1)([O-:3])=[O:2].[C:11](=O)([O-])[O-].[K+].[K+].CI>>[CH3:11][O:10][C:9]1[C:4]([N+:1]([O-:3])=[O:2])=[N:5][CH:6]=[CH:7][CH:8]=1

참가 물질

4

반응물 3

HCID 6328Methyl iodideHCID 11430Potassium CarbonateHCID 270573-Hydroxy-2-nitropyridine

생성물 1

HCID 5560633-Methoxy-2-nitropyridine수율 97.4%

실험 절차

The similar reaction as described in Reference Example 9 by using 2-nitro-3-hydroxypyridine (7.0 g), potassium carbonate (6.91 g) and methyl iodide (4.67 ml) gave the title compound (7.5 g) as crystalline powders.

후처리

  1. customThe similar reaction

출처 및 근거

ORD 기록
ord-5fbd7c38c66248e587ceea4b3a00c236
출처 데이터셋
uspto-grants-2016_05
특허 번호
US09346822B2

연결된 노트

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