Hydrochloric Acid → Diethyl 2-acetoxymethylimidazole-4,5-dicarboxylate

반응식

[C:1]([O:4][CH2:5][C:6]1[N:7](CC2C=CC=CC=2)[C:8]([C:16]([O:18][CH2:19][CH3:20])=[O:17])=[C:9]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[N:10]=1)(=[O:3])[CH3:2].Cl>>[C:1]([O:4][CH2:5][C:6]1[NH:10][C:9]([C:11]([O:13][CH2:14][CH3:15])=[O:12])=[C:8]([C:16]([O:18][CH2:19][CH3:20])=[O:17])[N:7]=1)(=[O:3])[CH3:2]

참가 물질

반응물 2

HCID 313Hydrochloric Acid

HCID 19036167Diethyl 2-acetoxymethyl-1-benzylimidazole-4,5-dicarboxylate

생성물 1

HCID 19036206Diethyl 2-acetoxymethylimidazole-4,5-dicarboxylate

실험 절차

Following a procedure similar to that described in Preparation 42(iv), but using 2.00 g of diethyl 2-acetoxymethyl-1-benzylimidazole-4,5-dicarboxylate [prepared as described in step (i) above] as a starting material, 1.70 g of the hydrochloride of the title compound were obtained as a syrup.

후처리

customprepared

출처 및 근거

ORD 기록: ord-466c54d6b0f24cbfb5b07d0d1c74a302
출처 데이터셋: uspto-grants-1997_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05616599

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