Hydrochloric Acid → Hydrochloric Acid

HRID 530840노트

반응식

HRID 530840 반응식
[F:1][C:2]1[CH:23]=[CH:22][CH:21]=[CH:20][C:3]=1[CH2:4][C:5]1([OH:19])[CH2:10][CH2:9][CH2:8][CH:7]([NH:11]C(=O)OC(C)(C)C)[CH2:6]1.[ClH:24]>O1CCOCC1>[ClH:24].[NH2:11][CH:7]1[CH2:8][CH2:9][CH2:10][C:5]([CH2:4][C:3]2[CH:20]=[CH:21][CH:22]=[CH:23][C:2]=2[F:1])([OH:19])[CH2:6]1

참가 물질

5

반응물 2

HCID 313Hydrochloric AcidHCID 67983409Tert-butyl 3-(2-fluorobenzyl)-3-hydroxycyclohexylcarbamate

생성물 2

HCID 313Hydrochloric AcidHCID 679838413-Amino-1-(2-fluorobenzyl)cyclohexanol

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

tert-Butyl 3-(2-fluorobenzyl)-3-hydroxycyclohexylcarbamate was stirred in a solution of HCl in dioxane (4 M) at room temperature for one hour. The product, HCl salt of 3-amino-1-(2-fluorobenzyl)cyclohexanol, was obtained after evaporation of solvent.

출처 및 근거

ORD 기록
ord-1ba40411662c4db29ecd26b07214ba60
출처 데이터셋
uspto-grants-2016_05
특허 번호
US09351965B2

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