Hydrochloric Acid → Hydrochloric Acid

HRID 530894노트

반응식

HRID 530894 반응식
[CH2:1]([NH:8][C:9]1([CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=2[F:30])[CH2:14][CH2:13][CH2:12][CH:11]([NH:15]C(=O)OC(C)(C)C)[CH2:10]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:31]>O1CCOCC1>[ClH:31].[CH2:1]([NH:8][C:9]1([CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=2[F:30])[CH2:14][CH2:13][CH2:12][CH:11]([NH2:15])[CH2:10]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

5

반응물 2

HCID 313Hydrochloric AcidHCID 67983661Tert-butyl 3-(benzylamino)-3-(2-fluorobenzyl)cyclohexylcarbamate

생성물 2

HCID 313Hydrochloric AcidHCID 77454515N1-benzyl-1-(2-fluorobenzyl)cyclohexane-1,3-diamine

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

tert-butyl 3-(benzylamino)-3-(2-fluorobenzyl)cyclohexylcarbamate was stirred in a solution of HCl in dioxane (4 M) at room temperature for 5 hours. The product, HCl salt of N1-benzyl-1-(2-fluorobenzyl)cyclohexane-1,3-diamine, was obtained after evaporation of solvent.

출처 및 근거

ORD 기록
ord-8097c30470ab4d3f9414952fc6b4833d
출처 데이터셋
uspto-grants-2016_05
특허 번호
US09351965B2

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