Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
tert-Butyl 2-(5-fluoro-2-nitrophenoxy)propylcarbamate → tert-Butyl 2-(2-amino-5-fluorophenoxy)propylcarbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | tert-Butyl 2-(5-fluoro-2-nitrophenoxy)propylcarbamate | HCID 58413346 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | tert-Butyl 2-(2-amino-5-fluorophenoxy)propylcarbamate | HCID 58413393 | — |
반응 단계
To a solution of tert-butyl 2-(5-fluoro-2-nitrophenoxy)propylcarbamate (3.1 g) in MeOH (5 ml) was added 10% palladium on carbon (300 mg) and the reaction mixture was hydrogenated at room temperature at 50 psi. The catalyst was filtered off and the filtrate was concentrated in vacuo.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08853193B2 |
| 출처 데이터셋 | uspto-grants-2014_10 |
| ORD ID | ord-be0d9773c66443df96f624b4727ffac0 |
| 출처 메모 | uspto-grants-2014_10 |