Acetic Anhydride → N-(5-Bromopyrazin-2-YL)acetamide

HRID 534144

반응식

HRID 534144 반응식
[NH2:1][C:2]1[CH:7]=[N:6][C:5]([Br:8])=[CH:4][N:3]=1.[C:9](OC(=O)C)(=[O:11])[CH3:10]>>[Br:8][C:5]1[N:6]=[CH:7][C:2]([NH:1][C:9](=[O:11])[CH3:10])=[N:3][CH:4]=1

참가 물질

3

반응물 2

HCID 7918Acetic AnhydrideHCID 5995392-Amino-5-bromopyrazine

생성물 1

HCID 58574049N-(5-Bromopyrazin-2-YL)acetamide

실험 절차

2-Amino-5-bromopyrazine (500 mg, 2.87 mmol) is stirred in acetic anhydride (5 mL) for 12 h at RT. The resulting solid is filtered off, digested with toluene and dried.

후처리

  1. filtrationThe resulting solid is filtered off
  2. customdried

출처 및 근거

ORD 기록
ord-22fb100ef5fa4ca2a71637b33257398e
출처 데이터셋
uspto-grants-2014_10
특허 번호
US08853420B2

연결된 노트

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