Diisopropylethylamine → HCID 22060999, 화합물

HRID 534619

반응식

HRID 534619 반응식
Cl[C:2]1[N:7]=[C:6]([NH:8][C:9]2[CH:14]=[CH:13][C:12]3[O:15][CH2:16][CH2:17][O:18][C:11]=3[CH:10]=2)[C:5]([F:19])=[CH:4][N:3]=1.Cl.N[C:22]1[C:23]([CH3:29])=[CH:24][C:25]([OH:28])=[CH:26][CH:27]=1.C([N:33](C(C)C)CC)(C)C>>[CH2:17]1[CH2:16][O:15][C:12]2[CH:13]=[CH:14][C:9]([N:8]([C:27]3[CH:22]=[C:23]([CH3:29])[CH:24]=[C:25]([OH:28])[CH:26]=3)[C:6]3[C:5]([F:19])=[CH:4][N:3]=[C:2]([NH2:33])[N:7]=3)=[CH:10][C:11]=2[O:18]1

참가 물질

4

반응물 3

HCID 81531DiisopropylethylamineHCID 4592344-Amino-M-cresol hydrochlorideHCID 220603622-chloro-5-fluoro-N-(3,4-ethylenedioxyphenyl)-4-pyrimidineamine

생성물 1

HCID 22060999HCID 22060999, 화합물

실험 절차

In like manner to the preparation of 5-fluoro-N4-(3-hydroxyphenyl)-N2-[4-(3-phenyl-1,2,4-oxadiazol-5-yl)methyleneoxyphenyl]-2,4-pyrimidinediamine, 2-chloro-N4-(3,4-ethylenedioxyphenyl)-5-fluoro-4-pyrimidineamine, 4-amino-m-cresol hydrogenchloride salt, and diisopropylethylamine were reacted to provide N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N4-(3-hydroxy-5-methylphenyl)-2,4-pyrimidinediamine.

후처리

  1. customwere reacted

출처 및 근거

ORD 기록
ord-fd079e27fe094e7c8503b6ed7de32730
출처 데이터셋
uspto-grants-2014_10
특허 번호
US08853397B2

연결된 노트

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