Bromomethylcyclopropane → 1-Cyclopropylmethylcytosine

HRID 538233노트

반응식

HRID 538233 반응식
N1C=CC(N)=NC1=O.BrCC1CC1.[NH2:14][C:15]1[CH:20]=[CH:19][N:18]([CH2:21][C:22]2[CH:27]=[CH:26]C=CC=2)[C:17](=[O:28])[N:16]=1>>[NH2:14][C:15]1[CH:20]=[CH:19][N:18]([CH2:21][CH:22]2[CH2:27][CH2:26]2)[C:17](=[O:28])[N:16]=1

참가 물질

4

반응물 3

HCID 81503BromomethylcyclopropaneHCID 3085814-Amino-1-benzylpyrimidin-2(1H)-oneHCID 178418229Cytosine

생성물 1

HCID 214443201-Cyclopropylmethylcytosine

실험 절차

4-Amino-1-cyclopropylmethyl-1H-pyrimidin-2-one was prepared from cytosine and (bromomethyl)cyclopropane using the methods described above for the preparation of 4-amino-1-benzyl-1H-pyrimidin-2-one.

출처 및 근거

ORD 기록
ord-04e04d6499cb496d9cb2bef4d74f79e7
출처 데이터셋
uspto-grants-2014_10
특허 번호
US08865725B2

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