1-Bromopentane → N-allyl-N-pentylphenylamine

HRID 53865

반응식

HRID 53865 반응식
[CH2:1]([NH:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH:2]=[CH2:3].Br[CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[OH-].[Na+]>O>[CH2:1]([N:4]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH:2]=[CH2:3]

참가 물질

5

반응물 3

HCID 80571-BromopentaneHCID 14798Sodium HydroxideHCID 68525N-Allylaniline

생성물 1

HCID 10608235N-allyl-N-pentylphenylamine수율 56.2%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

N-Allylphenylamine (1.95 g, 14.7 mmol) and bromopentane (2.22 g, 14.7 mmol) were stirred at 80° C. for 16 hours. After cooled to room temperature, the mixture was treated with a solution of sodium hydroxide(714 mg, 17.9 mmol) in water (1.5 ml), stirred for 30 minutes and extracted with ether (80 ml). The extract was dried over potassium carbonate, filterd and concentrated in vacuum. The residue was chromatographed on silica gel to give N-allyl-N-pentylphenylamine (1.68 g) in 56% yield as a colorless oil.

후처리

  1. extractionextracted with ether (80 ml)
  2. dry with materialThe extract was dried over potassium carbonate, filterd
  3. concentrationconcentrated in vacuum
  4. customThe residue was chromatographed on silica gel

출처 및 근거

ORD 기록
ord-90f2201b01fd4803b47ce102150f4fd9
출처 데이터셋
uspto-grants-1997_04
특허 번호
US05621084

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