Acetic Acid → N-Benzylacetamide

HRID 538954

반응식

HRID 538954 반응식
[CH2:1]([NH2:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:9](O)(=[O:11])[CH3:10]>>[C:9]([NH:8][CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)(=[O:11])[CH3:10]

참가 물질

3

반응물 2

HCID 176Acetic AcidHCID 7504Benzylamine

생성물 1

HCID 11500N-Benzylacetamide

반응 조건

온도
115 °C

실험 절차

Benzylamine (1 mL) and acetic acid (20 mL) may be mixed together. The mixture may be heated at 115° C. for 17 hours. The excess acetic acid may be distilled from the reaction mixture using a rotary evaporator. The product may be crystallized from toluene. The mixture may be cooled to 0° C. and then filtered.

후처리

  1. distillationThe excess acetic acid may be distilled from the reaction mixture
  2. customa rotary evaporator
  3. customThe product may be crystallized from toluene
  4. temperatureThe mixture may be cooled to 0° C.
  5. filtrationfiltered

출처 및 근거

ORD 기록
ord-27a2c44870504edb8d0db479262b468b
출처 데이터셋
uspto-grants-2014_10
특허 번호
US08865920B2

연결된 노트

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