Isobutyryl chloride → 5-Methyl-1-((3,4,5,6-tetrahydro-2H-pyran-2-yl)oxy)-2-hexyn-4-one

반응식

[C:1](Cl)(=[O:5])[CH:2]([CH3:4])[CH3:3].[CH2:7]([O:10][CH:11]1[CH2:16][CH2:15][CH2:14][CH2:13][O:12]1)[C:8]#[CH:9]>>[CH3:3][CH:2]([CH3:4])[C:1](=[O:5])[C:9]#[C:8][CH2:7][O:10][CH:11]1[CH2:16][CH2:15][CH2:14][CH2:13][O:12]1

참가 물질

반응물 2

HCID 62325Isobutyryl chloride

HCID 98609Tetrahydro-2-(2-propynyloxy)-2H-pyran

생성물 1

HCID 232495965-Methyl-1-((3,4,5,6-tetrahydro-2H-pyran-2-yl)oxy)-2-hexyn-4-one

실험 절차

The desired compound was prepared from isobutyryl chloride and 3,4,5,6-tetrahydro-2-(2-propynyloxy)-2H-pyran by analogy to the procedure of Tohda, et. al. (Synthesis, 777 (1977)).

출처 및 근거

ORD 기록: ord-78d8b486add6459a91602683db1d668f
출처 데이터셋: uspto-grants-1997_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05621109

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