Hydrogen Bromide → 6-(Aminomethyl)pyridin-2(1H)-one hydrobromide

HRID 542263노트

반응식

HRID 542263 반응식
[NH2:1][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([O:9]C)[N:4]=1.[BrH:11]>>[BrH:11].[NH2:1][CH2:2][C:3]1[NH:4][C:5](=[O:9])[CH:6]=[CH:7][CH:8]=1

참가 물질

3

반응물 2

HCID 260Hydrogen BromideHCID 13882973(6-Methoxypyridin-2-yl)methanamine

생성물 1

HCID 135635896-(Aminomethyl)pyridin-2(1H)-one hydrobromide

실험 절차

The crude product from Example 2 was combined with 10 ml of 48% hydrobromic acid, and the resulting mixture was heated at its reflux temperature for one hour. Evaporation to dryness provided 6-aminomethyl-2(1H)-pyridone hydrobromide as a water-soluble solid. The structural assignment was supported by infrared and nuclear magnetic resonance spectral analyses.

후처리

  1. temperaturethe resulting mixture was heated at its
  2. temperaturereflux temperature for one hour
  3. customEvaporation to dryness

출처 및 근거

ORD 기록
ord-1a9f767402184eff825e95da8669c952
출처 데이터셋
uspto-grants-1987_04
특허 번호
US04656285

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