Hydrogen Bromide → HCID 21242911, 화합물

반응식

COC1C=C(SC)C2CCN(C)CCC=2C=1.Cl.C[O:19][C:20]1[CH:21]=[C:22]([S:32]([CH3:35])(=[O:34])=[O:33])[C:23]2[CH2:29][CH2:28][N:27]([CH3:30])[CH2:26][CH2:25][C:24]=2[CH:31]=1.[BrH:36]>>[BrH:36].[OH:19][C:20]1[CH:21]=[C:22]([S:32]([CH3:35])(=[O:34])=[O:33])[C:23]2[CH2:29][CH2:28][N:27]([CH3:30])[CH2:26][CH2:25][C:24]=2[CH:31]=1

참가 물질

반응물 3

HCID 260Hydrogen Bromide

HCID 21242913HCID 21242913, 화합물

HCID 21242957HCID 21242957, 화합물

생성물 1

HCID 21242911HCID 21242911, 화합물

실험 절차

Following the procedure of Example 4, 8-methoxy-3-methyl-6-methylthio-2,3,4,5-tetrahydro-1H-3-benzazepine is converted to 8-methoxy-3-methyl-6-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride which is treated with hydrobromic acid to give 8-hydroxy-3-methyl-6-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide.

출처 및 근거

ORD 기록: ord-fdd6668823924c0cb0fd4363e0a1f6e1
출처 데이터셋: uspto-grants-1987_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04659706

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