Ethanol → 4-dimethylamino-N'-(4-nitrophenyl)-benzenecarbohydrazonamide

HRID 542875노트

반응식

HRID 542875 반응식
[CH3:1][N:2]([CH3:21])[C:3]1[CH:8]=[CH:7][C:6]([C:9](=S)[NH:10]C2C=CC([N+]([O-])=O)=CC=2)=[CH:5][CH:4]=1.[CH2:22](O)[CH3:23].[OH2:25].[NH2:26][NH2:27].[OH2:28]>>[CH3:1][N:2]([CH3:21])[C:3]1[CH:4]=[CH:5][C:6]([C:9](=[N:26][NH:27][C:23]2[CH:22]=[CH:8][C:3]([N+:2]([O-:28])=[O:25])=[CH:4][CH:5]=2)[NH2:10])=[CH:7][CH:8]=1

참가 물질

5

반응물 4

HCID 702EthanolHCID 962WaterHCID 24654Hydrazine hydrate (1:1)HCID 131748644-dimethylamino-N-(4-nitrophenyl)-benzenecarbothiamide

생성물 1

HCID 540281914-dimethylamino-N'-(4-nitrophenyl)-benzenecarbohydrazonamide

반응 조건

온도
10 °C

실험 절차

A suspension of 30 g of the product of Step A and 180 ml of ethanol was heated to reflux and 30 ml of hydrazine hydrate were added thereto. The mixture was refluxed for 15 minutes and then 180 ml of distilled water were added thereto. The mixture was cooled to 10° C. and was vacuum filtered. The product was washed with water and dried to obtain 19 g of 4-dimethylamino-N'-(4-nitrophenyl)-benzenecarbohydrazonamide melting at 174° C.

후처리

  1. temperaturewas heated
  2. temperatureto reflux
  3. temperatureThe mixture was refluxed for 15 minutes
  4. filtrationfiltered
  5. washThe product was washed with water
  6. customdried

출처 및 근거

ORD 기록
ord-672695e7844a49fd90d3b7875e88e393
출처 데이터셋
uspto-grants-1987_04
특허 번호
US04659729

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