Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Norpyridostigmine → 3-(Dimethylcarbamoyloxy)-1-(hexanoyloxymethyl)-pyridinium chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Norpyridostigmine | HCID 98821 | — |
| 반응물 | Chloromethyl hexanoate | HCID 525229 | — |
| 생성물 | 3-(Dimethylcarbamoyloxy)-1-(hexanoyloxymethyl)-pyridinium chloride | HCID 20205836 | 80.2% |
반응 단계
3-Dimethylcarbamoyloxypyridine (1.66 g) and chloromethylhexanoate (2.0 g) were heated to 90° C. with stirring for 3 hours. The reaction mixture was treated in a similar manner as described in Example 1 to give 2.65 g of 3-(dimethylcarbamoyloxy)-1-(hexanoyloxymethyl)-pyridinium chloride as colorless powdery crystals. It was impossible to precisely measure the melting point because of high hygroscopicity. The structure was determined by N.M.R.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04661502 |
| 출처 데이터셋 | uspto-grants-1987_04 |
| ORD ID | ord-390da6494e7b419eac2dc5ef8c661421 |
| 출처 메모 | uspto-grants-1987_04 |