Potassium Carbonate → HCID 21294045, 화합물

HRID 543226노트

반응식

HRID 543226 반응식
Br[CH:2]([CH2:11][CH2:12][CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][C:7]([O:9]C)=[O:8].[CH3:14][CH2:15][CH2:16][C:17]1[C:22]([OH:23])=[C:21]([C:24]([CH3:26])=[O:25])[CH:20]=[CH:19][C:18]=1[OH:27].C(=O)([O-])[O-].[K+].[K+].[OH-].[Na+]>C(O)C.CC(C)=O>[C:24]([C:21]1[CH:20]=[CH:19][C:18]([O:27][CH:2]([CH2:11][CH2:12][CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][C:7]([OH:9])=[O:8])=[C:17]([CH2:16][CH2:15][CH3:14])[C:22]=1[OH:23])(=[O:25])[CH3:26]

참가 물질

7

반응물 4

HCID 11430Potassium CarbonateHCID 14798Sodium HydroxideHCID 27751982',4'-Dihydroxy-3'-propylacetophenoneHCID 21294048HCID 21294048, 화합물

생성물 1

HCID 21294045HCID 21294045, 화합물

시약·촉매·용매 2

HCID 180Acetone용매HCID 702Ethanol용매

실험 절차

Following the procedures of Examples 15 E and 15F, 1.18 g. of methyl 6-bromo-nonanoate and 0.91 g. of 2,4-dihydroxy-3-propylacetophenone were reacted in the presence of 0.65 g. of potassium carbonate in 40 ml. of acetone. Hydrolysis of the ester intermediate with sodium hydroxide in aqueous ethanol gave the title product, M+ =350; NMR.

출처 및 근거

ORD 기록
ord-4c3ae2b8cc054269baaf62d1ca5cc75c
출처 데이터셋
uspto-grants-1987_04
특허 번호
US04661505

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