1,3-Dichloro-2-butene → (6-benzoyl-2-pyridyl)methyl 2-[N-(2-chloro-2-propenyl)amino]-3-methylbutanoate

HRID 543905

반응식

HRID 543905 반응식
[NH2:1][CH:2]([CH:21]([CH3:23])[CH3:22])[C:3]([O:5][CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([C:13](=[O:20])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:8]=1)=[O:4].[Cl:24][C:25](=[CH2:28])[CH2:26]Br.[Cl:29][C:30]([CH3:34])=[CH:31][CH2:32]Cl>>[Cl:24][C:25](=[CH2:26])[CH2:28][NH:1][CH:2]([CH:21]([CH3:23])[CH3:22])[C:3]([O:5][CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([C:13](=[O:20])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:8]=1)=[O:4].[Cl:29][C:30]([CH3:34])=[CH:31][CH2:32][NH:1][CH:2]([CH:21]([CH3:23])[CH3:22])[C:3]([O:5][CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([C:13](=[O:20])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:8]=1)=[O:4]

참가 물질

5

반응물 3

HCID 135561,3-Dichloro-2-buteneHCID 2351213-Bromo-2-chloroprop-1-eneHCID 20461184(6-Benzoyl-2-pyridyl)methyl 2-amino-3-methylbutanoate

생성물 2

HCID 20461185(6-benzoyl-2-pyridyl)methyl 2-[N-(2-chloro-2-propenyl)amino]-3-methylbutanoateHCID 54537610(6-benzoyl-2-pyridyl)methyl 2-[N-(3-chloro-2-butenyl)amino]-3-methylbutanoate

실험 절차

Using the method of Example 2, (6-benzoyl-2-pyridyl)methyl 2-amino-3-methylbutanoate is reacted with each of 2-chloro-2-propen-1-yl bromide and 3-chloro-2-buten-1-yl chloride to yield (6-benzoyl-2-pyridyl)methyl 2-[N-(2-chloro-2-propenyl)amino]-3-methylbutanoate and (6-benzoyl-2-pyridyl)methyl 2-[N-(3-chloro-2-butenyl)amino]-3-methylbutanoate.

출처 및 근거

ORD 기록
ord-2b493799415144a5a9877d7c4423cd41
출처 데이터셋
uspto-grants-1984_05
특허 번호
US04447613

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