Water → Ethyl 2-(2-aminothiazol-4-yl)-2-cyclohexyloxyiminoacetate
반응식
Cl[CH2:2][C:3](=O)[C:4](=[N:10][O:11][CH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)[C:5]([O:7][CH2:8][CH3:9])=[O:6].[NH2:19][C:20]([NH2:22])=[S:21].O>C(O)C>[NH2:22][C:20]1[S:21][CH:2]=[C:3]([C:4](=[N:10][O:11][CH:12]2[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]2)[C:5]([O:7][CH2:8][CH3:9])=[O:6])[N:19]=1참가 물질
5
실험 절차
Ethyl 4-chloro-2-cyclohexyloxyimino-3-oxobutyrate (syn isomer, 27.8 g.), thiourea (7.7 g.), sodium acetate 3-hydrate (13.7 g.), water (70 ml.) and ethanol (140 ml.) were treated in a similar manner to that of Example F-(3) to give ethyl 2-(2-aminothiazol-4-yl)-2-cyclohexyloxyiminoacetate (syn isomer, 3.6 g.), mp. 125° to 126° C.
출처 및 근거
- ORD 기록
- ord-efb7b58854bb4715b16a807cf10fe822
- 출처 데이터셋
- uspto-grants-1984_05
- 특허 번호
- US04447430
반응 노트
불러오는 중…