Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Fluorophenyl isothiocyanate → 2'-Fluoro-4-(2-pyrazinyl)-1-piperazinethiocarboxanilide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Fluorophenyl isothiocyanate | HCID 97520 | — |
| 반응물 | 1-Piperazinylpyrazine | HCID 2734639 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 2'-Fluoro-4-(2-pyrazinyl)-1-piperazinethiocarboxanilide | HCID 13318694 | — |
반응 단계
To a solution of 4.92 g. of 1-(2-pyrazinyl)piperazine in 50 ml. of anhydrous ether is added a solution of 4.59 g. of 2-fluorophenyl isothiocyanate in 50 ml. of anhydrous ether over a period of 10 minutes. The mixture is stirred for 30 minutes and the resulting solid is collectedand then recrystallized from 200 ml. of ethanol, giving 7.04 g. of the desired product, m.p. 151°-153° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04450272 |
| 출처 데이터셋 | uspto-grants-1984_05 |
| ORD ID | ord-b8ccbe605ef04daf82a06593a3331c0c |
| 출처 메모 | uspto-grants-1984_05 |