N-bromobutanimide → 2-(Bromomethyl)-3-chloro-1,1'-biphenyl

HRID 544674

반응식

HRID 544674 반응식
[Cl:1][C:2]1[C:3]([CH3:14])=[C:4]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[Br:15]N1C(=O)CCC1=O>C(Cl)(Cl)(Cl)Cl>[Br:15][CH2:14][C:3]1[C:2]([Cl:1])=[CH:7][CH:6]=[CH:5][C:4]=1[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1

참가 물질

4

반응물 2

HCID 67184N-bromobutanimideHCID 46018323-Chloro-2-methylbiphenyl

생성물 1

HCID 133207002-(Bromomethyl)-3-chloro-1,1'-biphenyl

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

A mixture of 3-chloro-2-methyl[1,1'-biphenyl] (10.4 grams, 0.051 mole) and N-bromosuccinimide (9.2 grams, 0.052 mole) in carbon tetrachloride (150 ml) was heated and irradiated with an infrared lamp for two hours. The mixture was cooled and filtered. The filtrate was evaporated under reduced pressure to give a quantitative yield of 2-bromomethyl-3-chloro[1,1'-biphenyl] as a yellow oil.

후처리

  1. temperaturewas heated
  2. customirradiated with an infrared lamp for two hours
  3. temperatureThe mixture was cooled
  4. filtrationfiltered
  5. customThe filtrate was evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-c6f05b515ffa4cb4b7c949cce15d8276
출처 데이터셋
uspto-grants-1984_05
특허 번호
US04451484

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