Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Imidazole → HCID 19959422, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Imidazole | HCID 795 | — |
| 반응물 | 2-Bromo-1-(5-chloropyridin-2-yl)ethan-1-one hydrobromide | HCID 19959414 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | HCID 19959422 | HCID 19959422 | — |
반응 단계
15 g of 2-bromoacetyl-5-chloropyridine hydrobromide are dissolved in 50 ml of dry dichloromethane, 9.7 g of imidazole are added and the mixture is stirred for 24 hours at room temperature. Evaporation of the solvent in vacuo and subsequent chromatography of the residue over silicagel (dichloromethane/methanol/heptane=7/1/4) yield the compound as a cream coloured solid; m.p.: 122°-129°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05622982 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-d144c05ae6ae4a7bbc14d81edc48c273 |
| 출처 메모 | uspto-grants-1997_04 |