반응식
[OH:1][CH2:2][C@H:3]1[O:7][CH2:6][C@@H:5]([S:8][C:9](=[O:11])[CH3:10])[CH2:4]1.O.ClC(Cl)(Cl)[C:15]([N:17]=C=O)=[O:16]>C(Cl)Cl.C(O)(=O)C.[F-].C([N+](CCCC)(CCCC)CCCC)CCC.O1CCCC1>[NH2:17][C:15]([O:1][CH2:2][C@H:3]1[O:7][CH2:6][C@@H:5]([S:8][C:9](=[O:11])[CH3:10])[CH2:4]1)=[O:16]참가 물질
8
반응물 3
생성물 1
시약·촉매·용매 4
실험 절차
The title compound is prepared by the procedure of Example 7 using 0.28 g of product from Example 9 in 20 ml of methylene chloride, 0.208 ml of trichloroacetyl isocyanate, 0.80 ml of acetic acid, 6.79 ml of 1M tetrabutylammonium fluoride in tetrahydrofuran and 0.37 ml of water to give 0.320 g of the desired product.
출처 및 근거
- ORD 기록
- ord-5ce210a07f8045098a967abf4013a763
- 출처 데이터셋
- uspto-grants-1997_04
- 특허 번호
- US05623081
연결된 노트
불러오는 중…